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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCAM All Species: 23.03
Human Site: S603 Identified Species: 50.67
UniProt: P43121 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43121 NP_006491.2 646 71607 S603 Q E I T L P P S R K S E L V V
Chimpanzee Pan troglodytes XP_001149681 1230 134039 S1187 Q E I T L P P S R K S E F V V
Rhesus Macaque Macaca mulatta XP_001096935 753 82173 S710 Q E I T L P P S R K S E F V V
Dog Lupus familis XP_546486 813 88440 S770 Q E I T L P P S R K S E F V V
Cat Felis silvestris
Mouse Mus musculus Q8R2Y2 648 71527 T605 Q E I T L P P T R K S E F V V
Rat Rattus norvegicus Q9EPF2 648 71309 T605 Q E I T L P P T R K S E F V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517756 394 43137 R352 R H R L P C S R G E K G T P N
Chicken Gallus gallus P42292 588 65708 G536 D Q A K L I V G I V V G L L L
Frog Xenopus laevis NP_001085893 605 65914 S563 G K L T C G S S E K Q S L A Q
Zebra Danio Brachydanio rerio Q90460 564 61255 L516 I V G V V V G L F L A A A L V
Tiger Blowfish Takifugu rubipres NP_001092127 575 62314 L530 L L V A A V V L G L A Y W V Y
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.8 81.6 65.4 N.A. 76.2 75.3 N.A. 23.2 25.8 31.8 24.9 25.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 52.2 83.5 69.9 N.A. 87.5 87.3 N.A. 33.1 45.9 48.4 43.3 43 N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 86.6 86.6 N.A. 0 13.3 26.6 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 13.3 33.3 40 26.6 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 0 0 0 0 0 19 10 10 10 0 % A
% Cys: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 55 0 0 0 0 0 0 10 10 0 55 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 46 0 0 % F
% Gly: 10 0 10 0 0 10 10 10 19 0 0 19 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 55 0 0 10 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 10 0 0 0 0 0 64 10 0 0 0 0 % K
% Leu: 10 10 10 10 64 0 0 19 0 19 0 0 28 19 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 10 55 55 0 0 0 0 0 0 10 0 % P
% Gln: 55 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % Q
% Arg: 10 0 10 0 0 0 0 10 55 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 46 0 0 55 10 0 0 0 % S
% Thr: 0 0 0 64 0 0 0 19 0 0 0 0 10 0 0 % T
% Val: 0 10 10 10 10 19 19 0 0 10 10 0 0 64 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _